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Publications

28. Synthesis of a Functionalized Bicyclo[3.2.1]Octane: A Common Subunit to Kauranes, Grayananes, and Gibberellanes

N. Fay, C. Benbouziyane, C. Kouklovsky, A. de la Torre*, Chem. Eur. J. 2025, 31, e02441

Synthesis of a bicyclo[3.2.1]octane

27. Chemoselective Double Allylic Substitutions with Carbon Nucleophiles: Access to Tetrahydroindoles and Tetrahydrocarbazoles

B. Chen, L. Pagès, C. Kouklovsky, S. Prévost, A. de la Torre*, J. Org. Chem. 2025, 90, 6079–6083

Double allylic substitutions by dual catalysis

26. Regio- and Chemoselective Double Allylic Substitution of Alkenyl vic-Diols

B. Chen, L. Pagès, R. Dollet, C. Kouklovsky, S. Prévost, A. de la Torre*, Org. Lett. 2024, 26, 2393–2397

Highlighted in Org. Chem. Highlights, January 13 2025.

Synthesis of tetrahydrocarbazoles

25. Total Synthesis of Lucidumone: Attempted Shortcuts, Dead Ends and Lessons Learnt

G. Huang, A. Laporte, L. Pagès, C. Kouklovsky, A. de la Torre*, Synthesis 2024, 56, 1585-1592

Invited article for the Bürgenstock Special Section 2023 – Future Stars in Organic Chemistry

Synthesis of lucidumone

24. Natural Product Synthesis: The Endless Quest for Unreachable Perfection

N. Fay, C. Kouklovsky, A. de la Torre*, ACS Org. Inorg. Au 2023, 3, 350-363

Invited Perspective for the 2023 Rising Stars in Organic and Inorganic Chemistry special collection

Total synthesis

23. Retro-[4+2]/Intramolecular Diels–Alder Cascade Allows a Concise Total Synthesis of Lucidumone

 

G. Huang, C. Kouklovsky, A. de la Torre*, Synlett 2023, 34, 1195-1199.

Concise synthesis of lucidumone

22. Total synthesis of grayanane natural products

 

N. Fay, R. Blieck, C. Kouklovsky, A. de la Torre*, Beilstein J. Org. Chem. 2022, 18, 1707-1719.

Grayananes

21. 1,2-Boronate Rearrangement: an Efficient Tool for the Opening, Functionalization and Formation of Strained Cycles

 

R. Blieck*, A. de la Torre*, Eur. J. Org. Chem. 2022, e202200920

Boronate rearrangements

20. Gram-Scale Enantioselective Synthesis of (+)-Lucidumone

 

G. Huang, C. Kouklovsky, A. de la Torre*, J. Am. Chem. Soc. 2022, 144, 17803-17807

Highlighted in Synfacts 2022, 18, 1278, ChemistryViews, September 29 2022, Org. Chem. Highlights, August 21 2023.

Gram scale enantioselective total synthesis of lucidumone

19. Diastereo- and Enantioselective Inverse-Electron-Demand Diels-Alder Cycloaddition between 2-Pyrones and Acyclic Enol Ethers

 

G. Huang, R. Guillot, C. Kouklovsky, B. Maryasin, A. de la Torre*, Angew. Chem. Int. Ed. 2022, 61, e202208185

Enantioselective IEDDA 2-pyrones

18. Inverse-Electron-Demand Diels-Alder Reactions of 2-Pyrones: Bridged Lactones and Beyond

 

G. Huang, C. Kouklovsky, A. de la Torre*, Chem. Eur. J. 2021, 27, 4760-4788

IEDDA 2-pyrones

Publications prior to ICMMO

17. PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluorescence Microscopy

I. Saridakis, M. Riomet, O. Belleza, G. Coussanes, N. Singer, N. Kastner, E. Smith, V. Tona, A. de la Torre, E. Lopes, P. Murcia, L. González, H. Sitte, N. Maulide, Angew. Chem. Int. Ed. 2024, 63, e202318127.

16. Total Synthesis of C30 Botryococcene and epi-Botryococcene by a Diastereoselective Ring Opening of Alkenylcyclopropanes

M. Cormier, A. de la Torre, I. Marek, Angew. Chem. Int. Ed. 2018, 57, 13237-13241.

 

15. History of Chemical Routes towards Cyclic Non-Enzymatic Oxygenated Metabolites of Polyunsaturated Fatty Acids

C. Oger, C. Cuyamendous, A. de la Torre, M. Candy, A. Guy, V. Bultel-Poncé, T. Durand, J.-M. Galano, Synthesis 2018, 50, 3257-3280.

14. C-H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity

D. O’Donovan, P. Aillard, M. Berger, A. de la Torre, D. Petkova, C. Knittl-Frank, D. Geerdink, M. Kaiser, N. Maulide, Angew. Chem.Int. Ed. 2018, 57, 10737-10741.

13. Ynamide Preactivation Allows a Regio- and Stereoselective Synthesis of α,β-Disubstituted Enamides

L. L. Baldassari, A. de la Torre, J. Li, D. S. Lüdtke, N. Maulide, Angew. Chem. Int. Ed. 2017, 56, 15723-15727.

12. Reversing Polarity: Carbonyl α-Aminations with Nitrogen Nucleophiles

A. de la Torre, V. Tona, N. Maulide, Angew. Chem. Int. Ed. 2017, 56, 12416-12423.

11. Flexible and Chemoselective Oxidation of Amides to α-Keto Amides and α-Hydroxy Amides

A. de la Torre, D. Kaiser, N. Maulide, J. Am. Chem. Soc. 2017, 139, 6578-6581.

 

10. Direct Regioselective Synthesis of Tetrazolium Salts by Activation of Secondary Amides under Mild Conditions

V. Tona, B. Maryasin, A. de la Torre, J. Sprachmann, L. González, N. Maulide, Org. Lett. 2017, 19, 2662-2665.

 

9. Metal-Free Formal Oxidative C-C Coupling by In Situ Generation of an Enolonium Species

D. Kaiser, A. de la Torre, S. Shaaban, N. Maulide, Angew. Chem. Int. Ed. 2017, 56, 5921-5925. Highlighted in Synfacts 2017, 13, 913.

 

8. The novelty of Phytofurans, Isofurans, Dihomo-Isofurans and Neurofurans: Discovery, Synthesis and Potential Application

C. Cuyamendous, A. de la Torre, K. S. Leung, A. Guy, V. Bultel-Poncé, J.-M. Galano, J. C.-Y. Lee, C. Oger, T. Durand, Biochimie 2016, 130, 49-62.

 

7. Benzoyl Shift: a New Approach to Reverse Regioselectivity in the Monoprotection of  vic-Diols

A. de la Torre, C. Oger, V. Bultel-Poncé, T. Durand, J.-M. Galano, Synlett 2016, 27, 2205-2208.

 

6. Recent Advances in the Synthesis of Tetrahydrofurans and Applications in Total Synthesis

A. de la Torre, C. Cuyamendous, T. Durand, J.-M. Galano, C. Oger, Tetrahedron 2016, 72, 5003-5025.

 

5. Chemo- and Stereoselective Transition Metal-Free Amination of Amides with Azides

V. Tona, A. de la Torre, M. Padmanaban, S. Ruider, L. González and N. Maulide, J. Am. Chem. Soc. 2016, 138, 8348-8351.

4. Total Syntheses and In Vivo Quantitation of Novel Neurofuran and Dihomo-isofuran Derived from Docosahexaenoic Acid and Adrenic Acid

A. de la Torre, Y. Y. Lee, A. Massoni, A. Guy, V. Bultel-Poncé, T. Durand, C. Oger, J. C.-Y. Lee, J.-M. Galano, Chem. Eur. J. 2015, 21, 2442.

Highlighted in Org. Chem. Highlights 2015, November 9.

 

3. Synthesis, discovery and quantitation of dihomo-Isofurans: novel biomarkers of in vivo adrenic acid peroxidation

A. de la Torre, Y. Y. Lee, C. Oger, P. T. Sangild, T. Durand, J. C.-Y. Lee, J.-M. Galano, Angew. Chem. Int. Ed. 2014, 53, 6249-6252.

Highlighted in Org. Chem. Highlights 2014, November 10.

 

2. Phytoprostanes, Isoprostanes and Neuroprostanes: The Lovely Story of n-3 and n-6 Polyunsaturated Fatty Acids Metabolites

J-M. Galano, C. Oger, A. de la Torre, C. Cuyamendous, V. Bultel-Poncé, A. Guy, G. Reversat, T. Durand, in Polyunsaturated fatty acids: Sources, Antioxidant Properties and Health Benefits, Nova Science Publishers, Inc., 2013.

 

1. Vestibulotoxic Properties of Potential Metabolites of Allylnitrile

F. Rua, M. Buffard, L. Sedo-Cabezon, G. Hernandez-Mir, A. de la Torre, S. Saldana-Ruiz, C. Chabbert, J. M. Bayona, A. Messeguer, J. Llorens, Toxicological Sciences 2013, 135, 182-192.

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